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Comment
. 2010 Jul 2;7(1):7-8.
doi: 10.1016/j.stem.2010.06.008.

Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs

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Matrix revolutions: a trinity of defined substrates for long-term expansion of human ESCs

Samira M Azarin et al. Cell Stem Cell. .
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Abstract

Recently in Nature Biotechnology, Rodin et al. (2010), Melkoumian et al. (2010), and Villa-Diaz et al. (2010) described defined, nonxenogenic substrates that support long-term self-renewal of human embryonic stem cells (hESCs). Used in conjunction with defined media, these substrates will facilitate expansion of hESCs for therapeutic applications.

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