doi: 10.1016/j.mimet.2010.07.001.
Epub 2010 Jul 16.
Helicobacter pylori bacterial ghost containing recombinant Omp18 as a putative vaccine
Affiliations
- PMID: 20621134
- DOI: 10.1016/j.mimet.2010.07.001
Item in Clipboard
Helicobacter pylori bacterial ghost containing recombinant Omp18 as a putative vaccine
J Microbiol Methods.
2010 Sep.
Abstract
Helicobacter pylori bacterial ghosts, HPBG, were generated by PhiX174 mechanism and loaded with recombinant Omp18, which were then applied in therapeutic immunization of Hp-infected C57BL/6 mice. Recombinant Omp18 loaded HPBG plus cholera toxin stimulated serum anti-Hp and Omp18-specific antibodies which resulted in significant reduction of gastric Hp colonization (P<0.05).
(c) 2010 Elsevier B.V. All rights reserved.
Similar articles
-
Recombinant Mycobacterium smegmatis mc(2)155 vaccine expressing outer membrane protein 26 kDa antigen affords therapeutic protection against Helicobacter pylori infection.Vaccine. 2009 Feb 11;27(7):972-8. doi: 10.1016/j.vaccine.2008.12.003. Epub 2008 Dec 25. Vaccine. 2009. PMID: 19111590
-
Evaluation of a new tumor necrosis factor-alpha-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen.Helicobacter. 2009 Oct;14(5):135-43. doi: 10.1111/j.1523-5378.2009.00713.x. Helicobacter. 2009. PMID: 19751439
-
Helicobacter pylori outer membrane protein 18 (Hp1125) induces dendritic cell maturation and function.Helicobacter. 2005 Oct;10(5):424-32. doi: 10.1111/j.1523-5378.2005.00350.x. Helicobacter. 2005. PMID: 16181353
-
Helicobacter pylori vaccine development: optimisation of strategies and importance of challenging strain and animal model.Int J Med Microbiol. 2008 Jan;298(1-2):151-9. doi: 10.1016/j.ijmm.2007.07.006. Epub 2007 Aug 21. Int J Med Microbiol. 2008. PMID: 17714988 Review.
-
Inflammation, immunity, and vaccine development for Helicobacter pylori.Helicobacter. 2011 Sep;16 Suppl 1:26-32. doi: 10.1111/j.1523-5378.2011.00877.x. Helicobacter. 2011. PMID: 21896082 Review.
Cited by
-
Burkholderia vaccines: are we moving forward?Front Cell Infect Microbiol. 2013 Feb 5;3:5. doi: 10.3389/fcimb.2013.00005. eCollection 2013. Front Cell Infect Microbiol. 2013. PMID: 23386999 Free PMC article. Review.
-
The Inhibitory Effect of Mouse Gastric DNA on Amplification of Helicobacter pylori Genomic DNA in Quantitative PCR.Iran Biomed J. 2019 Jul;23(4):297-302. doi: 10.29252/.23.4.297. Epub 2018 Jul 25. Iran Biomed J. 2019. PMID: 30041293 Free PMC article.
-
Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines.BMC Microbiol. 2018 Jul 28;18(1):80. doi: 10.1186/s12866-018-1216-6. BMC Microbiol. 2018. PMID: 30055567 Free PMC article.
-
Bio-inspired, bioengineered and biomimetic drug delivery carriers.Nat Rev Drug Discov. 2011 Jul 1;10(7):521-35. doi: 10.1038/nrd3499. Nat Rev Drug Discov. 2011. PMID: 21720407 Review.
-
A Novel and Efficient High-Yield Method for Preparing Bacterial Ghosts.Toxins (Basel). 2021 Jun 13;13(6):420. doi: 10.3390/toxins13060420. Toxins (Basel). 2021. PMID: 34199218 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous
