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. 2010 Jul;28(7):691-3.
doi: 10.1038/nbt0710-691.

Cloud computing and the DNA data race

Michael C Schatz  1 , Ben Langmead, Steven L Salzberg
Affiliations

Cloud computing and the DNA data race

Michael C Schatz et al. Nat Biotechnol. 2010 Jul.
No abstract available

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Figures

Figure 1
Figure 1. Map-Shuffle-Scan framework used by Crossbow
Users begin by uploading the sequencing reads into the cloud storage. Hadoop, running on a cluster of virtual machines in the cloud, then maps the unaligned reads to the reference genome using many parallel instances of Bowtie. Hadoop then automatically shuffles the alignments into sorted bins determined by chromosome region. Finally, many parallel instances of SOAPsnp scan the sorted alignments in each bin. The final output is a stream of SNP calls stored within the cloud that can be downloaded back to the user's local computer.
See this image and copyright information in PMC

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