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Review
. 2010 Aug;32(8):582-9.
doi: 10.1111/j.1365-3024.2010.01227.x.

Fact or hypothesis: concomitant immunity in taeniid cestode infections

M W Lightowlers  1
Affiliations
Free PMC article
Review

Fact or hypothesis: concomitant immunity in taeniid cestode infections

M W Lightowlers. Parasite Immunol. 2010 Aug.
Free PMC article

Abstract

Sustained research efforts over the last 50 years have revealed a considerable amount of information about immunity to taeniid cestode infections in the parasites' intermediate hosts. As a product of this research, a series of effective recombinant vaccines have been developed which have no parallel in any other group of parasitic organisms. There are, however, many important aspects relating to immunity that remain to be elucidated. Some concepts have come to be firmly held as facts and yet the supportive data are either conflicting or unconfirmed. This review considers the phenomenon of immunity to re-infection with taeniid cestodes in their intermediate hosts, examining carefully the nature of the evidence that is available to support conclusions that have been drawn in this area.

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References

    1. Miller HM. The production of artificial immunity in the albino rat to a metazoan parasite. J Prev Med. 1931;5:429–452.
    1. Lightowlers MW. Vaccines against cysticercosis and hydatidosis: foundations in taeniid cestode immunology. Parasitol Int. 2006;55(Suppl):S39–S43. - PubMed
    1. Rickard MD, Williams JF. Hydatidosis/cysticercosis: immune mechanisms and immunization against infection. Adv Parasitol. 1982;21:229–296. - PubMed
    1. Lightowlers MW. Cestode vaccines: origins, current status and future prospects. Parasitology. 2006;133(Suppl):S27–S42. - PubMed
    1. Assana E, Kyngdon CT, Gauci CG, et al. Elimination of Taenia solium transmission to pigs in a field trial of the TSOL18 vaccine in Cameroon. Int J Parasitol. 2010;40:515–519. in press. - PMC - PubMed

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