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Comment
. 2010 Jun 15;18(6):878-80.
doi: 10.1016/j.devcel.2010.06.001.

The DUBle life of polycomb complexes

Bernd Schuettengruber  1 , Giacomo Cavalli
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Free article
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The DUBle life of polycomb complexes

Bernd Schuettengruber et al. Dev Cell. .
Free article

Abstract

Many Polycomb group (PcG) proteins assemble into complexes containing histone-modifying enzymes that act in concert to control developmental regulators. In a recent study in Nature, Scheuermann et al. report the identification of a PcG complex with histone H2A-specific deubiquitinase activity that may be a key player in PcG-target gene regulation.

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