The development of the von Willebrand syndrome with the use of continuous flow left ventricular assist devices: a cause-and-effect relationship

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Leslie W Miller. J Am Coll Cardiol. 2010.

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. 2010 Oct 5;56(15):1214-5.

doi: 10.1016/j.jacc.2010.06.009. Epub 2010 Jul 12.

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Comment on

Extended mechanical circulatory support with a continuous-flow rotary left ventricular assist device.
Pagani FD, Miller LW, Russell SD, Aaronson KD, John R, Boyle AJ, Conte JV, Bogaev RC, MacGillivray TE, Naka Y, Mancini D, Massey HT, Chen L, Klodell CT, Aranda JM, Moazami N, Ewald GA, Farrar DJ, Frazier OH; HeartMate II Investigators. Pagani FD, et al. J Am Coll Cardiol. 2009 Jul 21;54(4):312-21. doi: 10.1016/j.jacc.2009.03.055. J Am Coll Cardiol. 2009. PMID: 19608028 Clinical Trial.
Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation.
Uriel N, Pak SW, Jorde UP, Jude B, Susen S, Vincentelli A, Ennezat PV, Cappleman S, Naka Y, Mancini D. Uriel N, et al. J Am Coll Cardiol. 2010 Oct 5;56(15):1207-13. doi: 10.1016/j.jacc.2010.05.016. Epub 2010 Jul 2. J Am Coll Cardiol. 2010. PMID: 20598466