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Case Reports
. 1978 Mar;8(2):195-201.
doi: 10.1111/j.1365-2222.1978.tb00464.x.

Recurrent nocturnal asthma due to tolylene di-isocyanate: a case report

Case Reports

Recurrent nocturnal asthma due to tolylene di-isocyanate: a case report

A Siracusa et al. Clin Allergy. 1978 Mar.

Abstract

In a carpenter with a history of nocturnal dyspnoea, a bronchial provocation test with a tolylene di-isocyanate (TDI) activator elicited a non-immediate asthmatic reaction, followed by recurrent nocturnal asthma for five subsequent nights. Subsequently, the study of the circadian rhythm of airflow, registered during work, confirmed the presence of recurrent nocturnal asthma of occupational origin.

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