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. 2009 Jun;53(3):281-93.

The microcirculation in sepsis

Asha Tyagi  1 , Ashok Kumar Sethi, Gautam Girotra, Medha Mohta
Affiliations

The microcirculation in sepsis

Asha Tyagi et al. Indian J Anaesth. 2009 Jun.

Abstract

Sepsis is a leading cause of mortality in critically ill patients. The pathophysiology of sepsis involves a highly complex and integrated response, including the activation of various cell types, inflammatory mediators, and the haemostatic system. Recent evidence suggests an emerging role of the microcirculation in sepsis, necessitating a shift in our locus away Irom the macrohaemodynamics to ill icrohaemodynanmics in a septic patient. This review article provides a brief overview of the microcirculation, its assessment techniques, and specific therapies to resuscitate the microhaemodynamics.

Keywords: Micro-haemodynamics; Microcirculation; Sepsis.

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References

    1. Angus DC, Wax RS. Epidemiology of sepsis: an update. Crit Care Med. 2001;29:S109–16. - PubMed
    1. Balestra GM, Legrand M, Ince C. Microcirculation and mitochondria in sepsis: getting out of breath. Curr Opin Anaesthesiol. 2009;22:184–90. - PubMed
    1. Conzen P, Vollmar B, Peter K. The Microcirculation. In: Prys-Roberts C, Brown BR Jr, editors. International Practice of Anaesthesia. Oxford: Butterworth Heinemann; 1996. pp. 1–19.
    1. De Backer D, Hollenberg S, Boerma C, et al. How to evaluate the microcirculation: report of a round table conference. Crit Care. 2007;11:R101. - PMC - PubMed
    1. Tsai AG, Johnson PC, Intaglietta M. Oxygen gradients in the microcirculation. Physiol Rev. 2003;83:933–63. - PubMed