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Comment
. 2010 Sep 15;16(18):4493-5.
doi: 10.1158/1078-0432.CCR-10-1548. Epub 2010 Jul 19.

Volumes to learn: advancing therapeutics with innovative computed tomography image data analysis

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Comment

Volumes to learn: advancing therapeutics with innovative computed tomography image data analysis

Michael L Maitland. Clin Cancer Res. .

Abstract

Semi-automated methods for calculating tumor volumes from computed tomography images are a new tool for advancing the development of cancer therapeutics. Volumetric measurements, relying on already widely available standard clinical imaging techniques, could shorten the observation intervals needed to identify cohorts of patients sensitive or resistant to treatment.

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Figures

Figure 1
Figure 1. Tumor volume change as an early response metric
Early response assessment is limited by smaller magnitude changes than seen with conventionally timed response assessment (top). Volume measurement may allow detection of antitumor effect when it is not apparent with conventional diameter measurement (bottom).

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References

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