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Review
. 2010 Aug;6(8):560-3.
doi: 10.1038/nchembio.408.

The chemical biology of synapses and neuronal circuits

Haruhiko Bito  1
Affiliations
Review

The chemical biology of synapses and neuronal circuits

Haruhiko Bito. Nat Chem Biol. 2010 Aug.

Abstract

Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have important biological consequences. Powerful chemical biological techniques have now been developed to decipher the dynamic stability of the synapses and to further interrogate the complex properties of neuronal circuits.

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