The chemical biology of synapses and neuronal circuits
- PMID: 20644538
- DOI: 10.1038/nchembio.408
The chemical biology of synapses and neuronal circuits
Abstract
Excitatory synapses are located in confined chemical spaces called the dendritic spines. These are atypical femtoliter-order microdomains where the behavior of even single molecules may have important biological consequences. Powerful chemical biological techniques have now been developed to decipher the dynamic stability of the synapses and to further interrogate the complex properties of neuronal circuits.
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