Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Aug;21(8):1247-53.
doi: 10.1681/ASN.2010060616. Epub 2010 Jul 22.

Resolved: EMT produces fibroblasts in the kidney

Michael Zeisberg  1 , Jeremy S Duffield
Affiliations

Resolved: EMT produces fibroblasts in the kidney

Michael Zeisberg et al. J Am Soc Nephrol. 2010 Aug.

Abstract

Epithelial-mesenchymal transition (EMT) is a mechanism for generating primitive mesenchymal cells during gastrulation or mobile tumor cells during cancer metastasis. For 15 years, EMT has also been viewed as a principal source of fibroblasts in tissue fibrosis. Because several recent studies question its role in fibrogenesis, it seems like a good time for debate.

PubMed Disclaimer

Publication types

LinkOut - more resources