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. 2009 Dec 22;1(1):100-104.
doi: 10.1159/000265699.

Anetoderma: Is It a Sign of Autoimmunity?

Hessa Al Buainain  1 , Mohamed Allam
Affiliations

Anetoderma: Is It a Sign of Autoimmunity?

Hessa Al Buainain et al. Case Rep Dermatol. .

Abstract

Anetoderma is a rare elastolytic disorder characterized by circumscribed areas of flaccid skin due to the loss of elastic tissue in the dermis. Primary anetoderma is frequently observed in patients with autoimmune diseases or abnormalities especially with antiphospholipid antibodies with or without antiphospholipid syndrome. In this case report we discuss a patient with primary anetoderma with positive antithyroid peroxidase antibodies, which is consistent with autoimmune thyroiditis.

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Figures

Fig. 1
Fig. 1
Multiple small circumscribed wrinkled sacs like lesions on the shoulders and upper back.
Fig. 2
Fig. 2
Minimal dermal perivascular chronic inflammatory cells infiltrate.
Fig. 3
Fig. 3
Elastic stain (Verhoef-Van Gieson) showing loss of elastic fibers in the superficial dermis.
See this image and copyright information in PMC

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