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. 2010 Jul 25:7:171.
doi: 10.1186/1743-422X-7-171.

High prevalence of porcine Hokovirus in German wild boar populations

Cornelia Adlhoch  1 , Marco Kaiser, Heinz Ellerbrok, Georg Pauli
Affiliations

High prevalence of porcine Hokovirus in German wild boar populations

Cornelia Adlhoch et al. Virol J. .

Abstract

Porcine Hokovirus (PHoV) was recently discovered in Hong Kong. This new Parvovirus of pigs is closely related to the human Parvoviruses 4 and 5 (PARV4/5) and bovine Hokovirus (BHoV). So far, nothing is known about the presence and prevalence of PHoV in regions of the world other than Hong Kong. A study was initiated to investigate PHoV in German wild boars from five different geographical regions, using a newly established quantitative real-time PCR assay. Analysis of collected liver and serum samples revealed high overall prevalence (32.7%; 51/156) of PHoV in wild boars. The prevalence differed between the regions and increased with age. Two near full-length genomes and a large fragment for three additional isolates from different regions were sequenced and used for phylogenetic analysis. The German PHoV sequences from wild boars showed a close relationship with sequences of isolates from Hong Kong.

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Figures

Figure 1
Figure 1
Phylogenetic analysis. A phylogenetic tree of new porcine, bovine and human parvoviruses was constructed using the neighbor joining method. Bootstrap values for the major branch points are given in percent. The trees were statistically evaluated in a bootstrap analysis with 1,000 replicates. The new German PHoV sequences are indicated with a dot.
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