Disseminated penicilliosis marneffei in China. Report of three cases

Abstract

Three cases with disseminated Penicilliosis marneffei (PSM) are reported. They are all natives of Guangxi Zhuang Autonomous Region. Among them, 2 died and 1 remains alive. Their clinical features were characterized by multiple organ involvement, multiple subcutaneous abscesses, inflammatory papules, nodules and pustulae, and enlargement of superficial lymph nodes with chills, fever, anemia and leukocytosis. The mycology and histopathology of PSM are also discussed. The authors propose that the medical profession in Guangxi should be vigilant against the disease and reduce the mortality by early diagnosis and treatment.