Comment
doi: 10.1016/j.cell.2010.07.001.
No bones about it: insulin modulates skeletal remodeling
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- PMID: 20655463
- DOI: 10.1016/j.cell.2010.07.001
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Comment
No bones about it: insulin modulates skeletal remodeling
Cell.
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Free article
Abstract
Advancing the hypothesis that bone remodeling is intimately linked to metabolic homeostasis, Fulzele et al. (2010) and Ferron et al. (2010) present evidence that insulin signaling promotes the activation of bone-forming osteoblasts and enhances production of osteocalcin, a secreted mediator of insulin sensitivity, through modulation of bone resorption.
Copyright 2010 Elsevier Inc. All rights reserved.
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