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Clinical Trial
. 1991 Mar;45(3):139-44.

A double-blind trial of zinc supplementation in pregnancy

Affiliations
  • PMID: 2065637
Clinical Trial

A double-blind trial of zinc supplementation in pregnancy

K Simmer et al. Eur J Clin Nutr. 1991 Mar.

Abstract

A double-blind randomised trial of oral zinc supplementation was carried out during the last two trimesters of pregnancy. Fifty-six women at risk of delivering a small-for-gestational-age baby received either zinc supplement (22.5 mg daily) or placebo. Twenty-nine of the women were compliant. Zinc significantly reduced the incidence of intrauterine growth retardation, and most measured indices of labour and fetal health were better in the supplemented group. Larger studies are now needed to confirm a role for selective zinc supplementation in at-risk pregnancies.

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