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. 1991 Jul 15;47(7):718-21.
doi: 10.1007/BF01958825.

EGF receptor induction and insulin-EGF overlap in Tetrahymena

G Csaba  1 , P Kovács
Affiliations

EGF receptor induction and insulin-EGF overlap in Tetrahymena

G Csaba et al. Experientia. .

Abstract

Offspring generations of Tetrahymena pretreated (imprinted) with insulin showed a greater binding capacity for the hormone than offspring of untreated ones. The epidermal growth factor (EGF) imprinted for insulin to a greater degree than insulin itself, and vice versa: insulin imprinted for EGF more efficiently than EGF itself. These phenomena can be explained by the overlap of insulin and EGF on one another's receptors in Tetrahymena.

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