Fructose: pure, white, and deadly? Fructose, by any other name, is a health hazard
- PMID: 20663467
- PMCID: PMC2909535
- DOI: 10.1177/193229681000400432
Fructose: pure, white, and deadly? Fructose, by any other name, is a health hazard
Abstract
The worldwide consumption of sucrose, and thus fructose, has risen logarithmically since 1800. Many concerns about the health hazards of calorie-sweetened beverages, including soft drinks and fruit drinks and the fructose they provide, have been voiced over the past 10 years. These concerns are related to higher energy intake, risk of obesity, risk of diabetes, risk of cardiovascular disease, risk of gout in men, and risk of metabolic syndrome. Fructose appears to be responsible for most of the metabolic risks, including high production of lipids, increased thermogenesis, and higher blood pressure associated with sugar or high fructose corn syrup. Some claim that sugar is natural, but natural does not assure safety.
2010 Diabetes Technology Society.
Figures
Similar articles
-
Energy and fructose from beverages sweetened with sugar or high-fructose corn syrup pose a health risk for some people.Adv Nutr. 2013 Mar 1;4(2):220-5. doi: 10.3945/an.112.002816. Adv Nutr. 2013. PMID: 23493538 Free PMC article. Review.
-
Fructose and Cardiometabolic Health: What the Evidence From Sugar-Sweetened Beverages Tells Us.J Am Coll Cardiol. 2015 Oct 6;66(14):1615-1624. doi: 10.1016/j.jacc.2015.08.025. J Am Coll Cardiol. 2015. PMID: 26429086 Free PMC article. Review.
-
Excess free fructose, high-fructose corn syrup and adult asthma: the Framingham Offspring Cohort.Br J Nutr. 2018 May;119(10):1157-1167. doi: 10.1017/S0007114518000417. Epub 2018 Mar 28. Br J Nutr. 2018. PMID: 29587887
-
Fructose: should we worry?Int J Obes (Lond). 2008 Dec;32 Suppl 7:S127-31. doi: 10.1038/ijo.2008.248. Int J Obes (Lond). 2008. PMID: 19136981 Review.
-
Soft drinks, fructose consumption, and the risk of gout in men: prospective cohort study.BMJ. 2008 Feb 9;336(7639):309-12. doi: 10.1136/bmj.39449.819271.BE. Epub 2008 Jan 31. BMJ. 2008. PMID: 18244959 Free PMC article.
Cited by
-
Sex differences in renal and metabolic responses to a high-fructose diet in mice.Am J Physiol Renal Physiol. 2015 Mar 1;308(5):F400-10. doi: 10.1152/ajprenal.00403.2014. Epub 2014 Dec 23. Am J Physiol Renal Physiol. 2015. PMID: 25537743 Free PMC article.
-
Early and sustained exposure to high-sucrose diet triggers hippocampal ER stress in young rats.Metab Brain Dis. 2016 Aug;31(4):917-27. doi: 10.1007/s11011-016-9830-1. Epub 2016 May 7. Metab Brain Dis. 2016. PMID: 27154727
-
The effects of fructose-containing sugars on weight, body composition and cardiometabolic risk factors when consumed at up to the 90th percentile population consumption level for fructose.Nutrients. 2014 Aug 8;6(8):3153-68. doi: 10.3390/nu6083153. Nutrients. 2014. PMID: 25111121 Free PMC article. Clinical Trial.
-
The effect of normally consumed amounts of sucrose or high fructose corn syrup on lipid profiles, body composition and related parameters in overweight/obese subjects.Nutrients. 2014 Mar 17;6(3):1128-44. doi: 10.3390/nu6031128. Nutrients. 2014. PMID: 24642950 Free PMC article. Clinical Trial.
-
Added sugars and risk factors for obesity, diabetes and heart disease.Int J Obes (Lond). 2016 Mar;40 Suppl 1:S22-7. doi: 10.1038/ijo.2016.10. Int J Obes (Lond). 2016. PMID: 27001643 Review.
References
-
- Yudkin J. Pure, White and Deadly. London: Penguin Books; 1989.
-
- Bray GA, Nielsen SJ, Popkin BM. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Am J Clin Nutr. 2004;79(4):537–543. - PubMed
-
- Mintz S. Sweetness and power: the place of sugar in history. London: Penguin Books; 1986.
-
- Appel LJ, Moore TJ, Obarzanek E, Vollmer W, Svetkey LP, Sacks FM, Bray GA, Vogt TM, Cutler JA, Windhauser MM, Lin PH, Karanja N. A clinical trial of the effects of dietary patterns on blood pressure. New Engl J Med. 1997;336(16):1117–1124. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous