Follow-up Study after Intracranial Percutaneous Transluminal Cerebral Balloon Angioplasty

Abstract

To find the angiographic lesions specific characteristics appropriate for intracranial percutaneous transluminal cerebral angioplasty (PTCBA). Forty-two clinically symptomatic patients with 42 haemodynamically significant intracranial lesions (% diameter stenosis > 70) were treated by PTCBA between January 1992 and May 1996. Before the angioplasty treatment, the patients were classified into three groups according to the angiographic lesions' characteristics summarised as follows: type A, a short and concentric stenosis; type B, a tubular lesion, or an extreme eccentric lesion; and type C, a diffuse lesion. They were followed after PTCBA from one month to six years to compare between the three groups. Primary end points were death, stroke, or bypass surgery. The clinical success rates in type A, B and C groups were 92%, 86% and 33% (p=0.0032), respectively. Cumulative risks of fatal or nonfatal ischaemic stroke / ipsilateral bypass surgery in type A, B and C groups were 8%, 26% and 87% (p < 0.0001), respectively. The cumulative risk of 8% in type A group patients appeared to be smaller than in historical studies. PTCBA for intracranial simple (type A) lesions produces a favourable clinical outcome for symptomatic patients.