Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 Sep;24(3):619-38.
doi: 10.1016/j.idc.2010.04.009.

Severe acute respiratory syndrome and coronavirus

David S C Hui  1 , Paul K S Chan
Affiliations
Review

Severe acute respiratory syndrome and coronavirus

David S C Hui et al. Infect Dis Clin North Am. 2010 Sep.

Abstract

Severe acute respiratory syndrome (SARS) is a highly infectious disease with a significant morbidity and mortality. Respiratory failure is the major complication, and patients may progress to acute respiratory distress syndrome. Health care workers are particularly vulnerable to SARS. SARS has the potential of being converted from droplet to airborne transmission. There is currently no proven effective treatment of SARS, so early recognition, isolation, and stringent infection control are the key to controlling this highly contagious disease. Horseshoe bats are implicated in the emergence of novel coronavirus infection in humans. Further studies are needed to examine host genetic markers that may predict clinical outcome.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Thoracic HRCT of a patient with SARS showing typical early changes with solitary ground-glass opacification at the left lower lobe.
See this image and copyright information in PMC

References

    1. Lee N., Hui D.S., Wu A. A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med. 2003;348:1986–1994. - PubMed
    1. Hsu L.Y., Lee C.C., Green J.A. Severe acute respiratory syndrome in Singapore: clinical features of index patient and initial contacts. Emerg Infect Dis. 2003;9:713–717. - PMC - PubMed
    1. Booth C.M., Matukas L.M., Tomlinson G.A. Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA. 2003;289:2801–2809. - PubMed
    1. Twu S.J., Chen T.J., Chen C.J. Control measures for severe acute respiratory syndrome (SARS) in Taiwan. Emerg Infect Dis. 2003;9:718–720. - PMC - PubMed
    1. WHO Summary of probable SARS cases with onset of illness from 1 November to 31 July 2003. http://www.who.int/csr/sars/country/table2003_09_23/en Available at: Accessed September 23, 2003.

MeSH terms