Diminished renal function and the incidence of heart failure
- PMID: 20676281
- PMCID: PMC2822145
- DOI: 10.2174/157340309788970388
Diminished renal function and the incidence of heart failure
Abstract
Heart failure is one of the most common, costly, disabling and deadly diseases. During the last decade, several different indices reflecting renal function such as creatinine-based glomerular filtration rate, circulating levels of cystatin C and low-grade albuminuria have been demonstrated to be independent risk factors for heart failure. This review summarizes our current knowledge of the relationship between diminished renal function and the incidence of heart failure in the community, and also in individuals with increased risk of heart failure such as patients with overt cardiovascular disease, hypertension or diabetes. This review will also put forward important areas of future research in this field.
Keywords: Heart failure; albuminuria.; creatinine; cystatin C; glomerular filtration rate; kidney disease.
Figures
References
-
- Ronco C, House AA, Haapio M. Cardiorenal syndrome: Refining the definition of a complex symbiosis gone wrong. Intensive Care Med. 2008;34(5):957–62. - PubMed
-
- Hillege HL, Girbes AR, de Kam PJ, et al. Renal function, neurohormonal activation, and survival in patients with chronic heart failure. Circulation. 2000;102:203–10. - PubMed
-
- Hillege HL, Nitsch D, Pfeffer MA, et al. Renal function as a predictor of outcome in a broad spectrum of patients with heart failure. Circulation. 2006;113:671–8. - PubMed
-
- Bibbins-Domingo K, Lin F, Vittinghoff E, Barrett-Connor E, Grady D, Shlipak MG. Renal insufficiency as an independent predictor of mortality among women with heart failure. J Am Coll Cardiol. 2004;44:1593–600. - PubMed
-
- Shlipak MG, Smith GL, Rathore SS, Massie BM, Krumholz HM. Renal function, digoxin therapy, and heart failure outcomes: Evidence from the digoxin intervention group trial. J Am Soc Nephrol. 2004;15:2195–203. - PubMed
LinkOut - more resources
Full Text Sources
