Tumorigenesis: Might as well face it, you're addicted to MYC

Comment

Safia Ali Danovi. Nat Rev Cancer. 2010 Aug.

. 2010 Aug;10(8):532-3.

doi: 10.1038/nrc2908.

No abstract available

Comment on

Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells.
Choi SH, Wright JB, Gerber SA, Cole MD. Choi SH, et al. Genes Dev. 2010 Jun 15;24(12):1236-41. doi: 10.1101/gad.1920310. Genes Dev. 2010. PMID: 20551172 Free PMC article.
The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance.
van Riggelen J, Müller J, Otto T, Beuger V, Yetil A, Choi PS, Kosan C, Möröy T, Felsher DW, Eilers M. van Riggelen J, et al. Genes Dev. 2010 Jun 15;24(12):1281-94. doi: 10.1101/gad.585710. Genes Dev. 2010. PMID: 20551174 Free PMC article.