Clozapine: Current perspective
- PMID: 20680140
- PMCID: PMC2910351
- DOI: 10.4103/0019-5545.37668
Clozapine: Current perspective
Abstract
The author conducted a review of studies that compared the efficacy, tolerability and indication for the use of clozapine in current perspectives for the treatment of resistant schizophrenia/ partial responders.
Keywords: Clozapine; SGA; resistant schizophrenia.
Conflict of interest statement
Similar articles
-
Adjunctive second-generation antipsychotics for specific symptom domains of schizophrenia resistant to clozapine: A meta-analysis.J Psychiatr Res. 2019 Jan;108:24-33. doi: 10.1016/j.jpsychires.2018.11.005. Epub 2018 Nov 3. J Psychiatr Res. 2019. PMID: 30447508
-
Lurasidone Augmentation of Clozapine in Refractory Schizophrenia: A Case Series.J Clin Psychopharmacol. 2023 Mar-Apr 01;43(2):157-160. doi: 10.1097/JCP.0000000000001662. J Clin Psychopharmacol. 2023. PMID: 36825872
-
Glutamatergic neurometabolites in clozapine-responsive and -resistant schizophrenia.Int J Neuropsychopharmacol. 2015 Jan 20;18(6):pyu117. doi: 10.1093/ijnp/pyu117. Int J Neuropsychopharmacol. 2015. PMID: 25603859 Free PMC article.
-
A randomized, double-blind comparison of clozapine and high-dose olanzapine in treatment-resistant patients with schizophrenia.J Clin Psychiatry. 2008 Feb;69(2):274-85. doi: 10.4088/jcp.v69n0214. J Clin Psychiatry. 2008. PMID: 18232726 Clinical Trial.
-
[Leponex, 10 years after -- a clinical review].Encephale. 2004 Sep-Oct;30(5):474-91. doi: 10.1016/s0013-7006(04)95462-0. Encephale. 2004. PMID: 15627052 Review. French.
Cited by
-
Clozapine-induced paralytic ileus: a case report.Ther Adv Psychopharmacol. 2014 Aug;4(4):170-2. doi: 10.1177/2045125314524980. Ther Adv Psychopharmacol. 2014. PMID: 25083276 Free PMC article. No abstract available.
-
Clozapine-Induced Febrile Neutropenia and Cellulitis.Turk J Emerg Med. 2016 Feb 26;14(1):41-3. doi: 10.5505/1304.7361.2014.83097. eCollection 2014 Mar. Turk J Emerg Med. 2016. PMID: 27331165 Free PMC article.
-
A new synthetic ultrasound-assisted method for dibenzoepines.Heliyon. 2023 Jul 14;9(7):e18319. doi: 10.1016/j.heliyon.2023.e18319. eCollection 2023 Jul. Heliyon. 2023. PMID: 37539205 Free PMC article.
-
Indian research on acute organic brain syndrome: Delirium.Indian J Psychiatry. 2010 Jan;52(Suppl 1):S139-47. doi: 10.4103/0019-5545.69226. Indian J Psychiatry. 2010. PMID: 21836671 Free PMC article.
-
Clozapine and neutrophil response in patients of African descent: A six-month, multinational, prospective, open-label clinical trial.Schizophr Res. 2024 Jun;268:312-322. doi: 10.1016/j.schres.2023.08.002. Epub 2023 Aug 24. Schizophr Res. 2024. PMID: 37633776 Free PMC article. Clinical Trial.
References
-
- Hippius H. The founding of the CINP and the discovery of clozapine. In: Healy D, editor. The psychopharmacologists. New York, NY: Chapman and Hall; 1996. pp. 185–213.
-
- Shen WW. Pharmacotherapy of schizophrenia: The American current status. Keio J Med. 1994;43:192–200. - PubMed
-
- Hippius H. The history of clozapine. Psychopharmacology. 1989;99:S3–5. - PubMed
-
- Gross H, Langner E. Effect profile of a chemically new broad spectrum neuroleptic of the dibenzo-diazepine group. Wien Med Wochenschr. 1966;116:814–6. - PubMed
-
- Bente D, Engelmeier M-P, Heinrich K, Schmitt W, Hippius H. Clinical studies with a neuroleptically active dibenzothiazepine derivative. Arzneimittelforschung. 1966;16:314–6. - PubMed