[Metagenomics opens up new frontiers in microbiology]
- PMID: 20681350
[Metagenomics opens up new frontiers in microbiology]
Abstract
Metagenomics can be described as genomics of all the microorganisms in a community. In recent years it has been applied to the study of microbial communities in soil and in human intestine, as an example. In metagenomics the microbial communities can be linked to their ecological roles and functions. Not only the species present in a sample are detected but the microbial communities are studied based on the whole genetic material. Thus novel genes, proteins and biochemical pathways are discovered. The sequencing technologies have developed rapidly within last years and this has enabled the study of genomes and metagenomes of individual organisms and whole communities, respectively, in reasonable time and with decreasing expenses.
Similar articles
-
High-resolution metagenomics targets specific functional types in complex microbial communities.Nat Biotechnol. 2008 Sep;26(9):1029-34. doi: 10.1038/nbt.1488. Nat Biotechnol. 2008. PMID: 18711340
-
Exploring research frontiers in microbiology: the challenge of metagenomics in soil microbiology.Res Microbiol. 2010 Jul-Aug;161(6):497-505. doi: 10.1016/j.resmic.2010.04.010. Epub 2010 May 7. Res Microbiol. 2010. PMID: 20452420 Review.
-
Metagenomics and biological ontology.Stud Hist Philos Biol Biomed Sci. 2007 Dec;38(4):834-46. doi: 10.1016/j.shpsc.2007.09.001. Epub 2007 Nov 19. Stud Hist Philos Biol Biomed Sci. 2007. PMID: 18053937 Review.
-
Mining genomes and 'metagenomes' for novel catalysts.Curr Opin Biotechnol. 2005 Dec;16(6):588-93. doi: 10.1016/j.copbio.2005.09.001. Epub 2005 Sep 19. Curr Opin Biotechnol. 2005. PMID: 16171989 Review.
-
Metagenomic studies reveal the critical and wide-ranging ecological importance of uncultivated Archaea: the role of ammonia oxidizers.Bioessays. 2007 Jan;29(1):11-4. doi: 10.1002/bies.20519. Bioessays. 2007. PMID: 17187352
Cited by
-
Metagenomics analysis of cocoa bean fermentation microbiome identifying species diversity and putative functional capabilities.Heliyon. 2019 Jul 30;5(7):e02170. doi: 10.1016/j.heliyon.2019.e02170. eCollection 2019 Jul. Heliyon. 2019. PMID: 31388591 Free PMC article.