Comment
doi: 10.1016/j.stem.2010.07.002.
Dying alone: a tale of rho
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- PMID: 20682437
- DOI: 10.1016/j.stem.2010.07.002
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Comment
Dying alone: a tale of rho
Cell Stem Cell.
.
Free article
Abstract
In this issue of Cell Stem Cell, Chen et al. (2010) and Ohgushi et al. (2010) report that Rho-mediated actomyosin contractility underlies the proclivity of human embryonic stem cells to undergo apoptosis upon dissociation or during low-density propagation, a property that challenges their in vitro isolation and manipulation.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells.Cell Stem Cell. 2010 Aug 6;7(2):225-39. doi: 10.1016/j.stem.2010.06.018. Cell Stem Cell. 2010. PMID: 20682448
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Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells.Cell Stem Cell. 2010 Aug 6;7(2):240-8. doi: 10.1016/j.stem.2010.06.017. Cell Stem Cell. 2010. PMID: 20682449 Free PMC article.
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