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doi: 10.1016/j.stem.2010.07.004.
Getting to the heart of the matter: direct reprogramming to cardiomyocytes
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- PMID: 20682439
- DOI: 10.1016/j.stem.2010.07.004
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Comment
Getting to the heart of the matter: direct reprogramming to cardiomyocytes
Cell Stem Cell.
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Free article
Abstract
Since MyoD was used to convert fibroblasts directly to skeletal muscle, biologists have tried to apply this strategy to generate other cell lineages. In their recent Cell paper, Ieda et al. (2010) use selected cardiac transcription factors to directly reprogram fibroblasts to cardiomyocytes without passing through an intervening pluripotent state.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.Cell. 2010 Aug 6;142(3):375-86. doi: 10.1016/j.cell.2010.07.002. Cell. 2010. PMID: 20691899 Free PMC article.
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