Evasion of natural killer cells by influenza virus
- PMID: 20682623
- PMCID: PMC3024901
- DOI: 10.1189/jlb.0610319
Evasion of natural killer cells by influenza virus
Abstract
NK cells are important innate immune effectors during influenza virus infection. However, the influenza virus seems able to use several tactics to counter NK cell recognition for immune evasion. In this review, we will summarize and discuss recent advances regarding the understanding of NK cell evasion mechanisms manipulated by the influenza virus to facilitate its rapid replication inside the respiratory epithelial cells.
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References
-
- Nelson M. I., Holmes E. C. (2007) The evolution of epidemic influenza. Nat. Rev. Genet. 8, 196–205 - PubMed
-
- Horimoto T., Kawaoka Y. (2005) Influenza: lessons from past pandemics, warnings from current incidents. Nat. Rev. Microbiol. 3, 591–600 - PubMed
-
- Hale B. G., Randall R. E., Ortin J., Jackson D. (2008) The multifunctional NS1 protein of influenza A viruses. J. Gen. Virol. 89, 2359–2376 - PubMed
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