Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Jul;30(7):2689-92.

MACC1 as a marker for advanced colorectal carcinoma

Atsushi Shirahata  1 , Kazuki Shinmura, Youhei Kitamura, Kazuma Sakuraba, Kazuaki Yokomizo, Tetsuhiro Goto, Hiroki Mizukami, Mitsuo Saito, Kazuyoshi Ishibashi, Gaku Kigawa, Hiroshi Nemoto, Kenji Hibi
Affiliations
  • PMID: 20682999

MACC1 as a marker for advanced colorectal carcinoma

Atsushi Shirahata et al. Anticancer Res. 2010 Jul.

Abstract

Background: Recently, Stein et al. identified the metastasis-associated in colon cancer 1 (MACC1) gene by genome-wide search for differentially expressed genes in human colon cancer tissues and metastases.

Patients and methods: We analyzed MACC1 expression levels in 52 colorectal cancer samples using quantitative real-time polymerase chain reaction (QRT-PCR).

Results: We found that MACC1 expression showed significant correlation with peritoneal dissemination (p=0.042) and higher stage of TNM classification (p=0.007).

Conclusion: These results suggest that MACC1 is more frequently expressed in advanced colorectal carcinomas.

PubMed Disclaimer

LinkOut - more resources