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. 1977 Dec:46:51-6.

Nomenclature for gliomas

F S Vogel
  • PMID: 206838

Nomenclature for gliomas

F S Vogel. Natl Cancer Inst Monogr. 1977 Dec.

Abstract

Gliomas, derived from astrocytes, oligodendroglia, or ependyma, are each united into a continuum by a graduation of anaplasia. Neoplasms originate at all levels of each continuum; subsequently, some move along its declivity. Conversely, neuroblastic tumors may differentiate, whereas concomitantly in the same lesion, the glial stroma may dedifferentiate. Anaplastic glia, as in a glioblastoma multiforme, can initiate malignant transformation in alien cells.

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