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Clinical Trial
. 1991 Jun 11;80(24):670-2.

[Efficacy and tolerance of cyclosporin A in the treatment of multiple sclerosis]

[Article in French]
M Schluep  1 , A J Steck, P A Despland, F Regli, F Ochsner, E Berrut, G Gauthier
Affiliations
  • PMID: 2068440
Clinical Trial

[Efficacy and tolerance of cyclosporin A in the treatment of multiple sclerosis]

[Article in French]
M Schluep et al. Schweiz Rundsch Med Prax. .

Abstract

The use and tolerance of cyclosporine A (Cy A) and azathioprine (AZA) are compared as long-term immunosuppression treatment for multiple sclerosis. 38 patients with multiple sclerosis were randomized and received either Cy A (5 mg/kg/d) or AZA (2 mg/kg/d) during 24 months. These patients were assessed clinically and with different biological parameters. The Cy A blood level was controlled, and Cy A was well tolerated without side effects forcing to stop the treatment. However, its benefits were limited when the different clinical scores are compared.

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