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. 2010 Aug 4:4:243.
doi: 10.1186/1752-1947-4-243.

High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case report

Frédéric Amant  1 , Kristel Van Calsteren, Maria Debiec-Rychter, Liesbeth Heyns, Katya Op De Beeck, Xavier Sagaert, Bart Bollen, Ignace Vergote
Affiliations

High-grade endometrial stromal sarcoma presenting in a 28-year-old woman during pregnancy: a case report

Frédéric Amant et al. J Med Case Rep. .

Abstract

Introduction: To the best of our knowledge, soft tissue sarcomas have not prevously been reported as a complication during pregnancy.

Case presentation: A 28-year-old Caucasian woman was diagnosed with a transperitoneal sarcoma during pregnancy. Morphological, immunohistochemical, chromosomal and mutational analyses pointed towards a high-grade endometrial stromal sarcoma. Although surgery and chemotherapy are possible during pregnancy, we were unable to perform these in this case.

Conclusion: The potential to treat gynecological cancer during pregnancy should always be assessed individually.

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Figures

Figure 1
Figure 1
Magnetic resonance imaging findings of diffuse peritoneal involvement by a poorly differentiated sarcoma. Sagittal T2-weighted turbo spin-echo magnetic resonance image (repetition time msec/echo time msec = 8440/136) shows diffuse sheetlike and nodular thickening of the peritoneal surfaces (arrows). Note also a moderate amount of ascites (asterisk). Bladder (B).
Figure 2
Figure 2
Peroperative findings indicating diffuse tumoral infiltration of the uterine serosa.
See this image and copyright information in PMC

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