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. 2010 Nov;63(11):1179-94.
doi: 10.1016/j.jclinepi.2010.04.011. Epub 2010 Aug 4.

The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008

David Cella  1 , William Riley, Arthur Stone, Nan Rothrock, Bryce Reeve, Susan Yount, Dagmar Amtmann, Rita Bode, Daniel Buysse, Seung Choi, Karon Cook, Robert Devellis, Darren DeWalt, James F Fries, Richard Gershon, Elizabeth A Hahn, Jin-Shei Lai, Paul Pilkonis, Dennis Revicki, Matthias Rose, Kevin Weinfurt, Ron Hays; PROMIS Cooperative Group
Affiliations

The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008

David Cella et al. J Clin Epidemiol. 2010 Nov.

Abstract

Objectives: Patient-reported outcomes (PROs) are essential when evaluating many new treatments in health care; yet, current measures have been limited by a lack of precision, standardization, and comparability of scores across studies and diseases. The Patient-Reported Outcomes Measurement Information System (PROMIS) provides item banks that offer the potential for efficient (minimizes item number without compromising reliability), flexible (enables optional use of interchangeable items), and precise (has minimal error in estimate) measurement of commonly studied PROs. We report results from the first large-scale testing of PROMIS items.

Study design and setting: Fourteen item pools were tested in the U.S. general population and clinical groups using an online panel and clinic recruitment. A scale-setting subsample was created reflecting demographics proportional to the 2000 U.S. census.

Results: Using item-response theory (graded response model), 11 item banks were calibrated on a sample of 21,133, measuring components of self-reported physical, mental, and social health, along with a 10-item Global Health Scale. Short forms from each bank were developed and compared with the overall bank and with other well-validated and widely accepted ("legacy") measures. All item banks demonstrated good reliability across most of the score distributions. Construct validity was supported by moderate to strong correlations with legacy measures.

Conclusion: PROMIS item banks and their short forms provide evidence that they are reliable and precise measures of generic symptoms and functional reports comparable to legacy instruments. Further testing will continue to validate and test PROMIS items and banks in diverse clinical populations.

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Figures

Figure 1
Figure 1
PROMIS Adult Health Domain Framework, March 2010
Figure 2
Figure 2
PROMIS Wave 1 Sample
See this image and copyright information in PMC

References

    1. Cella D, Yount S, Rothrock N, Gershon R, Cook K, Reeve B, et al. The Patient-Reported Outcomes Measurement Information System (PROMIS): Progress of an NIH Roadmap Cooperative Group During its First Two Years. Med Care. 2007;45(5 Suppl 1):S3–S11. - PMC - PubMed
    1. DeWalt DA, Rothrock N, Yount S, Stone AA. Evaluation of Item Candidates: The PROMIS Qualitative Item Review. Med Care. 2007;45(5 Suppl 1):S12–S21. - PMC - PubMed
    1. Castel LD, Williams KA, Bosworth HB, Eisen SV, Hahn EA, Irwin DE, et al. Content validity in the PROMIS social-health domain: A qualitative analysis of focus-group data. Qual Life Res. 2008;17(5):737–49. - PMC - PubMed
    1. Christodoulou C, Junghaenel DU, DeWalt DA, Rothrock N, Stone AA. Cognitive interviewing in the evaluation of fatigue items: Results from the patient-reported outcomes measurement information system (PROMIS) Qual Life Res. 2008;17(10):1239–46. - PMC - PubMed
    1. Reeve BB, Hays RD, Bjorner JB, Cook KF, Crane PK, Teresi JA, et al. Psychometric Evaluation and Calibration of Health-Related Quality of Life Item Banks: Plans for the Patient-Reported Outcomes Measurement Information System (PROMIS) Med Care. 2007;45(5 Suppl 1):S22–S31. - PubMed

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