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. 2010 Oct;48(10):3776-8.
doi: 10.1128/JCM.00472-10. Epub 2010 Aug 4.

Molecular Basis of pathogenicity in Helicobacter pylori clinical isolates

Ivy Bastos Ramis  1 , Tesiê Leopoldo Fonseca, Ernani Pinho de Moraes, Márcia Silveira Fernandes, Raul Mendoza-Sassi, Obirajara Rodrigues, Carlos Renan Varela Juliano, Carlos James Scaini, Pedro Eduardo Almeida da Silva
Affiliations

Molecular Basis of pathogenicity in Helicobacter pylori clinical isolates

Ivy Bastos Ramis et al. J Clin Microbiol. 2010 Oct.

Abstract

This study identified pathogenicity genes in 40 Helicobacter pylori clinical isolates. The cagA, vacA, and iceA genes were detected in 65%, 97.5%, and 97.5% of the isolates, respectively. The cagA, iceA1, and vacAs1a/m1 genes were related to erosive gastritis, whereas the vacAs2/m2 and iceA2 genes were associated with enanthematous gastritis.

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