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. 2010 Aug;58(8):1033-6.
doi: 10.1248/cpb.58.1033.

Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13

Jiraporn Arunpanichlert  1 , Vatcharin Rukachaisirikul, Yaowapa Sukpondma, Souwalak Phongpaichit, Supinya Tewtrakul, Nuttawut Rungjindamai, Jariya Sakayaroj
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Azaphilone and isocoumarin derivatives from the endophytic fungus Penicillium sclerotiorum PSU-A13

Jiraporn Arunpanichlert et al. Chem Pharm Bull (Tokyo). 2010 Aug.
Free article

Abstract

Two new azaphilone derivatives, penicilazaphilones A (1) and B (2), and one new isocoumarin, penicilisorin (3), together with six known compounds were isolated from the endophytic fungus Penicillium sclerotiorum PSU-A13. Their structures were identified by analysis of spectroscopic data. The antimicrobial activity against Staphylococcus aureus, Candida albicans and Cryptococcus neoformans as well as the inhibitory effect on human immunodeficiency virus (HIV)-1 integrase and protease were examined.

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