doi: 10.1038/nm0810-837a.
Big pharma moves from 'blockbusters' to 'niche busters'
- PMID: 20689537
- DOI: 10.1038/nm0810-837a
Item in Clipboard
Big pharma moves from 'blockbusters' to 'niche busters'
Nat Med.
2010 Aug.
No abstract available
Similar articles
-
Duel over discounts. Pharma, providers at odds over 'orphan drugs'.Mod Healthc. 2012 Jan 23;42(4):30-1. Mod Healthc. 2012. PMID: 22359763 No abstract available.
-
The European rare diseases therapeutic initiative.PLoS Med. 2005 Sep;2(9):e243. doi: 10.1371/journal.pmed.0020243. Epub 2005 Aug 23. PLoS Med. 2005. PMID: 16104832 Free PMC article.
-
Law and research could add up to profitable niche drugs.Nature. 2007 Apr 19;446(7138):856. doi: 10.1038/446856b. Nature. 2007. PMID: 17443162 No abstract available.
-
The evolving drug development landscape: from blockbusters to niche busters in the orphan drug space.Drug Dev Res. 2014 Jun;75(4):231-4. doi: 10.1002/ddr.21176. Epub 2014 May 14. Drug Dev Res. 2014. PMID: 24829189 Review.
-
Proposed 'grant-and-access' program with price caps could stimulate development of drugs for very rare diseases.Health Aff (Millwood). 2012 Nov;31(11):2528-35. doi: 10.1377/hlthaff.2012.0235. Health Aff (Millwood). 2012. PMID: 23129684 Review.
Cited by
-
Addressing the challenge of high-priced prescription drugs in the era of precision medicine: A systematic review of drug life cycles, therapeutic drug markets and regulatory frameworks.PLoS One. 2017 Aug 16;12(8):e0182613. doi: 10.1371/journal.pone.0182613. eCollection 2017. PLoS One. 2017. PMID: 28813502 Free PMC article.
-
Patient and interest organizations' views on personalized medicine: a qualitative study.BMC Med Ethics. 2016 May 13;17(1):28. doi: 10.1186/s12910-016-0111-7. BMC Med Ethics. 2016. PMID: 27178188 Free PMC article.
-
Drug pricing models, no 'one-size-fits-all' approach: a systematic review and critical evaluation of pricing models in an evolving pharmaceutical landscape.Eur J Health Econ. 2025 Jun;26(4):683-696. doi: 10.1007/s10198-024-01731-w. Epub 2024 Nov 4. Eur J Health Econ. 2025. PMID: 39495345 Free PMC article.
-
Why are our medicines so expensive? Spoiler: Not for the reasons you are being told….Eur J Gen Pract. 2024 Dec;30(1):2308006. doi: 10.1080/13814788.2024.2308006. Epub 2024 Feb 1. Eur J Gen Pract. 2024. PMID: 38299574 Free PMC article.
-
Points to consider: efficacy and safety evaluations in the clinical development of ultra-orphan drugs.Orphanet J Rare Dis. 2017 Aug 23;12(1):143. doi: 10.1186/s13023-017-0690-5. Orphanet J Rare Dis. 2017. PMID: 28835285 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
