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. 2010 Jul 30:4:717-24.
doi: 10.2147/opth.s10575.

Central corneal thickness and intraocular pressure in the Cameroonian nonglaucomatous population

André Omgbwa Eballe  1 , Godefroy Koki, Augustin Ellong, Didier Owono, Emilienne Epée, Lucienne Assumpta Bella, Côme Ebana Mvogo, Jeanne Mayouego Kouam
Affiliations

Central corneal thickness and intraocular pressure in the Cameroonian nonglaucomatous population

André Omgbwa Eballe et al. Clin Ophthalmol. .

Abstract

Aim: We performed a prospective, analytical study from 01 January to 31 March 2009 in the Ophthalmology Unit of the Gyneco-Obstetric and Pediatric Hospital of Yaounde, aiming to determine the profile of central corneal thickness (CCT) in the Cameroonian nonglaucomatous black population and its relationship with intraocular pressure (IOP).

Results and discussion: Four hundred and eighty-five patients (970 eyes) meeting our inclusion criteria were selected for this study. The average CCT was 529.29 +/- 35.9 mum in the right eye (95% confidence interval [CI]: 526.09-532.49), 528.19 +/- 35.9 mum in the left eye (95% CI: 524.99-531.40) and 528.74 +/- 35.89 mum in both eyes (95% CI: 526.48-531.00), range 440 to 670 mum. The average IOP was 13.01 +/- 2.97 mmHg in both eyes (95% CI: 12.82-13.19). A rise in CCT by 100 mum was followed by an increase in IOP of about 2.8 mmHg (95% CI: 2.3-3.6) for both eyes taken together. Linear regression analysis showed that corneal thickness was negatively correlated with age and IOP was positively related with age.

Conclusion: CCT in the Cameroonian nonglaucomatous black population was found to be lower compared with CCT values in Caucasian and Asian populations. On the basis of reference values ranging between 527 and 560 mum, an adjustment of IOP values by a correction factor is required for many Cameroonian patients. This will improve the diagnosis and follow-up of glaucoma by helping to detect true ocular hypertension.

Keywords: Cameroon; central corneal thickness; intraocular pressure.

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Figures

Figure 1
Figure 1
Intraocular pressure according to age (n = 970 eyes). Abbreviations: LE, left eye; RE, right eye.
Figure 2
Figure 2
Scattergramof central corneal thickness (CCT) versus age (n = 970 eyes).
Figure 3
Figure 3
Central corneal thickness according to age (n = 970 eyes). Abbreviations: LE, left eye; RE, right eye.
Figure 4
Figure 4
Intraocular pressure (IOP) according to central corneal thickness (CCT) in norm standards (n = 970 eyes). Abbreviations: LE, left eye; RE, right eye.
Figure 5
Figure 5
Scattergram between central corneal thickness (CCT) and intraocular pressure (IOP) (n = 970 eyes). Abbreviations: LE, left eye; RE, right eye.
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