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. 2010 Nov;28(9):963-8.
doi: 10.3109/07357907.2010.496759.

Population-based estimate of the prevalence of HER-2 positive breast cancer tumors for early stage patients in the US

Kathleen A Cronin  1 , Linda C Harlan, Kevin W Dodd, Jeffrey S Abrams, Rachel Ballard-Barbash
Affiliations

Population-based estimate of the prevalence of HER-2 positive breast cancer tumors for early stage patients in the US

Kathleen A Cronin et al. Cancer Invest. 2010 Nov.

Abstract

The goal of this study was to estimate prevalence of HER-2 positive tumors in a population-based sample of 1026 women diagnosed in 2005 with early stage breast cancer. We modeled the relationship between patient and tumor characteristics and HER-2. HER-2 positive estimates were 19% for women aged ≤ 49 years and 15% aged ≥ 50 years. HER-2 varied by tumor grade and size in women aged ≤ 49 years but was not significant in multivariate analysis. Tumor grade and race were associated with HER-2 for women aged ≥ 50 years after controlling for other variables. HER-2 varies by age and by race and tumor in older women.

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Conflict of interest statement

DECLARATION OF INTEREST The authors report no conflict of interest. The authors alone are responsible for the content and writing of this paper.

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