Review
doi: 10.1016/j.cell.2010.07.023.
A MAP for bundling microtubules
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- PMID: 20691897
- DOI: 10.1016/j.cell.2010.07.023
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Review
A MAP for bundling microtubules
Cell.
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Free article
Abstract
Microtubules assemble into arrays of bundled filaments that are critical for multiple steps in cell division, including anaphase and cytokinesis. Recent structural and functional studies, including two papers in this issue of Cell (Bieling et al., 2010; Subramanian et al., 2010), demonstrate how the MAP65 protein PRC1 crosslinks microtubules and cooperates with kinesin motors to control the dynamics and size of bundled regions.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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A minimal midzone protein module controls formation and length of antiparallel microtubule overlaps.Cell. 2010 Aug 6;142(3):420-32. doi: 10.1016/j.cell.2010.06.033. Cell. 2010. PMID: 20691901
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Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein.Cell. 2010 Aug 6;142(3):433-43. doi: 10.1016/j.cell.2010.07.012. Cell. 2010. PMID: 20691902 Free PMC article.
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