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. 2010 Sep 15;26(18):2361-2.
doi: 10.1093/bioinformatics/btq426. Epub 2010 Aug 6.

RefProtDom: a protein database with improved domain boundaries and homology relationships

Mileidy W Gonzalez  1 , William R Pearson
Affiliations

RefProtDom: a protein database with improved domain boundaries and homology relationships

Mileidy W Gonzalez et al. Bioinformatics. .

Abstract

RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications.

Availability: RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a.

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