Review
doi: 10.1097/PPO.0b013e3181eb3358.
Myeloid-derived suppressor cells in human cancer
Affiliations
- PMID: 20693846
- DOI: 10.1097/PPO.0b013e3181eb3358
Item in Clipboard
Review
Myeloid-derived suppressor cells in human cancer
Cancer J.
2010 Jul-Aug.
Abstract
Myeloid-derived suppressor cells are one of the major factors responsible for immune suppression in cancer. They also contribute to limited efficacy of current vaccination strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing primarily on the studies in cancer patients and current and future therapeutic options targeting these cells.
Similar articles
-
Myeloid derived suppressor cells and their role in tolerance induction in cancer.J Dermatol Sci. 2010 Jul;59(1):1-6. doi: 10.1016/j.jdermsci.2010.05.001. J Dermatol Sci. 2010. PMID: 20570112 Review.
-
Therapeutic targeting of myeloid-derived suppressor cells.Curr Opin Pharmacol. 2009 Aug;9(4):470-81. doi: 10.1016/j.coph.2009.06.014. Epub 2009 Jul 16. Curr Opin Pharmacol. 2009. PMID: 19616475 Review.
-
Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.Immunol Rev. 2008 Apr;222:162-79. doi: 10.1111/j.1600-065X.2008.00602.x. Immunol Rev. 2008. PMID: 18364001 Review.
-
Contribution of myeloid-derived suppressor cells to tumor-induced immune suppression, angiogenesis, invasion and metastasis.J Genet Genomics. 2010 Jul;37(7):423-30. doi: 10.1016/S1673-8527(09)60061-8. J Genet Genomics. 2010. PMID: 20659706
-
Myeloid-derived suppressor cell heterogeneity in human cancers.Ann N Y Acad Sci. 2014 Jun;1319:47-65. doi: 10.1111/nyas.12469. Ann N Y Acad Sci. 2014. PMID: 24965257 Review.
Cited by
-
TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions.PLoS One. 2015 Jan 28;10(1):e0117908. doi: 10.1371/journal.pone.0117908. eCollection 2015. PLoS One. 2015. PMID: 25629162 Free PMC article.
-
Immature myeloid cells in the tumor microenvironment: Implications for immunotherapy.Clin Immunol. 2018 Apr;189:34-42. doi: 10.1016/j.clim.2016.10.008. Epub 2016 Oct 21. Clin Immunol. 2018. PMID: 27777083 Free PMC article. Review.
-
The Yin and Yang of Myeloid Derived Suppressor Cells.Front Immunol. 2018 Nov 28;9:2776. doi: 10.3389/fimmu.2018.02776. eCollection 2018. Front Immunol. 2018. PMID: 30555467 Free PMC article. Review.
-
Blood biomarkers for canine cancer, from human to veterinary oncology.Vet Comp Oncol. 2022 Dec;20(4):767-777. doi: 10.1111/vco.12848. Epub 2022 Jul 20. Vet Comp Oncol. 2022. PMID: 35815441 Free PMC article. Review.
-
History of myeloid-derived suppressor cells.Nat Rev Cancer. 2013 Oct;13(10):739-52. doi: 10.1038/nrc3581. Nat Rev Cancer. 2013. PMID: 24060865 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
