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Review
. 2010 Oct;18(5):357-62.
doi: 10.1097/MOO.0b013e32833d11d9.

Cochlear otosclerosis

Sebahattin Cureoglu  1 , Muzeyyen Y Baylan, Michael M Paparella
Affiliations
Review

Cochlear otosclerosis

Sebahattin Cureoglu et al. Curr Opin Otolaryngol Head Neck Surg. 2010 Oct.

Abstract

Purpose of review: The aim of this study is to summarize current advances in research and clinical aspects of cochlear otosclerosis.

Recent findings: Recent studies have revealed that otosclerosis is a process of bone remodeling that is unique to the otic capsule only. Even though no obvious bone remodeling is seen in the otic capsule under normal conditions, remodeling starts when some molecular factors trigger the capsule in certain patients who have genetic and/or environmental tendencies.

Summary: Cochlear otosclerosis is defined as otosclerosis located in the otic capsule involving the cochlear endosteum and causing sensorineural hearing loss or mixed-type hearing loss. It has been clearly shown that, when otosclerosis is sufficiently severe to involve the cochlear endosteum, it usually fixes the stapes as well.

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Figures

Figure 1
Figure 1
a: Otosclerosis focus is involving cochlear endosteum and extending to the stapes footplate. 1b: A high magnification of the cochlear endosteum shows the hyalinization of the spiral ligament (*); and atrophy of the stria vascularis (arrow) (H&E staining).
Figure 1
Figure 1
a: Otosclerosis focus is involving cochlear endosteum and extending to the stapes footplate. 1b: A high magnification of the cochlear endosteum shows the hyalinization of the spiral ligament (*); and atrophy of the stria vascularis (arrow) (H&E staining).
Figure 2
Figure 2
a: Multiple otosclerotic foci involving stapes footplate and cochlear endosteum as well as blocking the vestibular aqueduct. 2b: a higher magnification of the rectangular area from figure 2a shows involvement of cochlear endosteum, hyalinization of the spiral ligament, and endolymphatic hydrops (H&E staining).
Figure 2
Figure 2
a: Multiple otosclerotic foci involving stapes footplate and cochlear endosteum as well as blocking the vestibular aqueduct. 2b: a higher magnification of the rectangular area from figure 2a shows involvement of cochlear endosteum, hyalinization of the spiral ligament, and endolymphatic hydrops (H&E staining).
See this image and copyright information in PMC

References

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