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Case Reports
. 2010 Aug;67(8):1012-5.
doi: 10.1001/archneurol.2010.187.

Bilateral pallidal stimulation for x-linked dystonia parkinsonism

Pettarusp M Wadia  1 , Shen-Yang Lim, Andres M Lozano, John R Adams, Yu-Yan Poon, Cristina V Torres Diaz, Elena Moro
Affiliations
Case Reports

Bilateral pallidal stimulation for x-linked dystonia parkinsonism

Pettarusp M Wadia et al. Arch Neurol. 2010 Aug.

Erratum in

  • Arch Neurol. 2011 Jun;68(6):724. Diaz, Cristina Torres [corrected to Torres Diaz, Cristina V]

Abstract

Objective: To report the clinical benefits of bilateral deep brain stimulation (DBS) of the globus pallidus internus (GPi) in a patient with X-linked dystonia parkinsonism (XDP).

Design: Case report.

Setting: Tertiary referral center. Patient A 40-year-old Filipino man with genetically confirmed XDP and severely disabling generalized dystonia. Intervention Bilateral GPi DBS.

Main outcome measures: The primary outcome measures were the Burke-Fahn-Marsden Dystonia Scale (BFMDS) severity and disability scores, and the secondary outcome measure was the Unified Parkinson Disease Rating Scores.

Results: At the 1-year postoperative follow-up, there was 80.4% improvement in the BFMDS severity score and 66.7% improvement in the BFMDS disability score.

Conclusion: Bilateral GPi DBS seems to be very effective in improving dystonia in XDP.

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