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Comparative Study
. 2010 Dec;14(6):1265-8.
doi: 10.1007/s10461-010-9768-y.

Biomarker testing to estimate under-reported heavy alcohol consumption by persons with HIV initiating ART in Uganda

Judith A Hahn  1 , Mwebesa B Bwana, Martin A Javors, Jeffrey N Martin, Nneka I Emenyonu, David R Bangsberg
Affiliations
Comparative Study

Biomarker testing to estimate under-reported heavy alcohol consumption by persons with HIV initiating ART in Uganda

Judith A Hahn et al. AIDS Behav. 2010 Dec.

Abstract

Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), a biomarker of heavy alcohol consumption, in persons initiating antiretroviral therapy in Uganda. Almost seven percent (6.7%) of persons reporting abstaining and 10% reporting consuming 1-40 drinks in the prior month tested positive for %CDT, and actual under-report may be higher due to low sensitivity of %CDT. These results suggest likely under-report in those reporting abstaining and current drinking. Improved identification of heavy alcohol consumption is needed for research and clinical purposes.

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