Review
doi: 10.1007/s11926-010-0121-2.
Remission in rheumatoid arthritis
Affiliations
- PMID: 20697983
- PMCID: PMC2927687
- DOI: 10.1007/s11926-010-0121-2
Item in Clipboard
Review
Remission in rheumatoid arthritis
Curr Rheumatol Rep.
2010 Oct.
Abstract
With advancing therapeutic options, achieving a state of remission has become the treatment goal in rheumatoid arthritis. Agreeing on what constitutes remission and what measures should be used to assess disease activity has remained a challenge. Multiple remission criteria have been devised and modified, all with different strengths and limitations. A consensus definition of remission will need to be achieved if we are to be able to evaluate outcomes of clinical trials and establish treatment targets for practice. Remission defined as the complete absence of disease currently may not be a realistic therapeutic goal.
Figures
Stringency of remission criteria for rheumatoid arthritis. US Food and Drug Administration (FDA) criteria are the most difficult to fulfill, whereas Disease Activity Score (DAS)28 criteria are the most inclusive. ACR—American College of Rheumatology; CDAI—Clinical Disease Activity Index; SDAI—Simplified Disease Activity Index
Similar articles
-
Progress toward the development of a new definition of remission in rheumatoid arthritis.Bull NYU Hosp Jt Dis. 2010;68(2):140-2. Bull NYU Hosp Jt Dis. 2010. PMID: 20632990
-
Patient perspective on remission in rheumatoid arthritis.J Rheumatol. 2011 Aug;38(8):1735-8. doi: 10.3899/jrheum.110394. J Rheumatol. 2011. PMID: 21807794
-
Should modern imaging be part of remission criteria in rheumatoid arthritis?Best Pract Res Clin Rheumatol. 2012 Dec;26(6):767-85. doi: 10.1016/j.berh.2012.10.004. Best Pract Res Clin Rheumatol. 2012. PMID: 23273791 Review.
-
Methods used to assess remission and low disease activity in rheumatoid arthritis.Autoimmun Rev. 2010 Jan;9(3):161-4. doi: 10.1016/j.autrev.2009.07.001. Epub 2009 Jul 19. Autoimmun Rev. 2010. PMID: 19602456 Review.
-
Implementation of a treat-to-target strategy in very early rheumatoid arthritis: results of the Dutch Rheumatoid Arthritis Monitoring remission induction cohort study.Arthritis Rheum. 2011 Oct;63(10):2865-72. doi: 10.1002/art.30494. Arthritis Rheum. 2011. PMID: 21647867
Cited by
-
Effect of Bizhongxiao decoction and its dismantled formulae on IL-1 and TNF levels in collagen-induced arthritis in rat synovial joints.Theor Biol Med Model. 2012 Nov 20;9:47. doi: 10.1186/1742-4682-9-47. Theor Biol Med Model. 2012. PMID: 23163934 Free PMC article.
-
Pain, sleep and emotional well-being explain the lack of agreement between physician- and patient-perceived remission in early rheumatoid arthritis.BMC Rheumatol. 2018 Jun 26;2:16. doi: 10.1186/s41927-018-0024-9. eCollection 2018. BMC Rheumatol. 2018. PMID: 30886967 Free PMC article.
-
Biologic Disease-Modifying Antirheumatic Drugs in a National, Privately Insured Population: Utilization, Expenditures, and Price Trends.Am Health Drug Benefits. 2017 Feb;10(1):27-36. Am Health Drug Benefits. 2017. PMID: 28465766 Free PMC article.
-
Achieving comprehensive disease control in patients with early and established rheumatoid arthritis treated with adalimumab plus methotrexate versus methotrexate alone.RMD Open. 2017 Sep 26;3(2):e000445. doi: 10.1136/rmdopen-2017-000445. eCollection 2017. RMD Open. 2017. PMID: 29018564 Free PMC article.
-
An association study of disease activity score components and patient satisfaction with overall health for early RA patients on non-biologic DMARD therapy.Rheumatol Int. 2012 Sep;32(9):2725-9. doi: 10.1007/s00296-011-2037-1. Epub 2011 Jul 30. Rheumatol Int. 2012. PMID: 21805175
References
-
- Paulus HE. Defining remission in rheumatoid arthritis: what is it? Does it matter? J Rheumatol. 2004;31:1–4. - PubMed
