doi: 10.1021/ja105245f.
Room temperature palladium-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids
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- PMID: 20698536
- DOI: 10.1021/ja105245f
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Room temperature palladium-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids
J Am Chem Soc.
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Abstract
A novel Pd-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids is realized at room temperature. This reaction provides efficient access to o-acyl acetanilides under mild conditions.