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. 2010 Sep 1;132(34):11898-9.
doi: 10.1021/ja105245f.

Room temperature palladium-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids

Ping Fang  1 , Mingzong Li, Haibo Ge
Affiliations

Room temperature palladium-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids

Ping Fang et al. J Am Chem Soc. .

Abstract

A novel Pd-catalyzed decarboxylative ortho-acylation of acetanilides with alpha-oxocarboxylic acids is realized at room temperature. This reaction provides efficient access to o-acyl acetanilides under mild conditions.

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