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. 2010 Sep;28(3):172-8.
doi: 10.3109/02813432.2010.506803.

Diastolic dysfunction is associated with sedentary leisure time physical activity and smoking in females only

Louise Bennet  1 , Charlotte Larsson, Marianne Söderström, Lennart Råstam, Ulf Lindblad
Affiliations

Diastolic dysfunction is associated with sedentary leisure time physical activity and smoking in females only

Louise Bennet et al. Scand J Prim Health Care. 2010 Sep.

Abstract

Objectives: Left ventricular diastolic dysfunction with preserved systolic function (DD-PSF) is associated with an increased risk of morbidity and mortality. Population-based surveys studying the associations between DD-PSF and lifestyle-associated risk factors, such as leisure time physical activity (LTPA) and smoking, are scarce. Thus, the aims were to explore the associations between DD-PSF and LTPA and smoking, employing optimal echocardiographic techniques.

Design: Cross-sectional study conducted from 2001 to 2003.

Setting: The study was conducted in a random sample of a rural Swedish population.

Subjects: Men and women of 30-75 years of age were consecutively invited for conventional echocardiography and tissue velocity imaging (n = 1149). Structured questionnaires and physical examinations were conducted using standardized methods.

Main outcome measures: DD-PSF was defined according to the European Society of Cardiology criteria excluding subjects with ejection fraction < 45%, or a self-reported history of heart failure.

Results: Complete information was available in 500 men and 538 women. In a multivariate model, DD-PSF was independently associated with sedentary LTPA and smoking in females; sedentary LTPA odds ratio (OR) 2.91, 95% confidence interval (CI) 1.02 to 8.27, and smoking OR 3.42, 95% CI 1.35 to 8.64. The probability of identifying DD-PSF in females with a sedentary LTPA was 37% and increased to 80% if they also had hypertension and were obese.

Conclusions: Sedentary LTPA and smoking are independently associated with DD-PSF in females. Identification of a sedentary lifestyle in females increases the probability of diagnosing DD-PSF.

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Figures

Figure 1.
Figure 1.
Prevalence of left ventricular diastolic dysfunction with preserved systolic function related to age and sex.
See this image and copyright information in PMC

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