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Review
. 2010 May-Jun;65(3):195-200.
doi: 10.2515/therapie/2010020. Epub 2010 Aug 11.

[Level of evidence for therapeutic drug monitoring for paclitaxel]

[Article in French]
Pauline Gerritsen-van Schieveen  1 , Bernard Royer; Suivi Thérapeutique Pharmacologique de la Société Française de Pharmacologie et de Thérapeutique
Affiliations
Review

[Level of evidence for therapeutic drug monitoring for paclitaxel]

[Article in French]
Pauline Gerritsen-van Schieveen et al. Therapie. 2010 May-Jun.

Abstract

Paclitaxel is an anticancer drug which displays pharmacokinetic properties which can lead to therapeutic drug monitoring requirement. The most effective pharmacokinetic parameter seems to be the time during which the plasma concentration is over 0.05 micromol/L. However, this target needs to be validated with new weekly schedules of administration. These reasons lead to consider the level of evidence of therapeutic drug monitoring of paclitaxel as potentially useful.

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