Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Sep 28;103(7):1085-8.
doi: 10.1038/sj.bjc.6605843. Epub 2010 Aug 10.

Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey

Z He  1 , Y Zhao, C Guo, Y Liu, M Sun, F Liu, X Wang, F Guo, K Chen, L Gao, T Ning, Y Pan, Y Li, S Zhang, C Lu, Z Wang, H Cai, Y Ke
Affiliations

Prevalence and risk factors for esophageal squamous cell cancer and precursor lesions in Anyang, China: a population-based endoscopic survey

Z He et al. Br J Cancer. .

Abstract

Background: The etiology of esophageal squamous cell cancer (ESCC) in high prevalence regions of China remains unclear.

Methods: Endoscopic biopsies were conducted among 7381 inhabitants aged from 25 to 65 of Anyang, China.

Results: In this study, 2.57, 0.20 and 0.16% of the participants had mild, moderate and severe squamous dysplasia, respectively; 0.19 and 0.08% showed squamous carcinoma in situ and invasive ESCC. Using deep well (depth >100 meters) as water source (odds ratio=0.72, 95% confidence interval: 0.54-0.96) was negatively associated with ESCC and its precursors, whereas tobacco and alcohol use were not significantly associated with ESCC.

Conclusions: Water source and other factors in this region need further evaluation by longitudinal studies.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(A) Detection rates of esophageal cancer and precursor lesions by age. (B) Detection rates of esophageal cancer and precursor lesions by gender.
See this image and copyright information in PMC

References

    1. Abnet CC, Qiao YL, Dawsey SM, Dong ZW, Taylor PR, Mark SD (2005) Tooth loss is associated with increased risk of total death and death from upper gastrointestinal cancer, heart disease, and stroke in a Chinese population-based cohort. Int J Epidemiol 34: 467–474 - PubMed
    1. Abnet CC, Qiao YL, Mark SD, Dong ZW, Taylor PR, Dawsey SM (2001) Prospective study of tooth loss and incident esophageal and gastric cancers in China. Cancer Causes Control 12: 847–854 - PubMed
    1. Adami H, Hunter D, Trichopoulos D (2002) Textbook of Cancer Epidemiology. Oxford University Press: Oxford
    1. Ahmad OB, Boschi-Pinto C, Lopez AD, Murray CJ, Lozano R, Inoue M (2000) Age standardization of rates: a new WHO standard In GPE Discussion Paper Series: No31 World Health Orgnization
    1. Blot WJ, Li JY (1985) Some considerations in the design of a nutrition intervention trial in Linxian, People’s Republic of China. Natl Cancer Inst Monogr 69: 29–34 - PubMed

Publication types